RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-142a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; MTT ASSAY etc.
Target
HMGB1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-142-3p inhibits hypoxia/reoxygenation-induced apoptosis and fibrosis of cardiomyocytes by targeting high mobility group box 1
Year
2016
Function
"miR-142-3p inhibits h/r-induced apoptosis and fibrosis of cardiomyocytes, partly at least, by the direct inhibition of HMGB1 expression."